CREB

CREB (cAMP-responsive element binding Protein)

  • alters the transcription of genes: increase in so-called immediate early genes
  • induces a neurochemical cascade that underlies memory formation.
  • then: retrograde signal (presumably via NO)
  • is a transcription factor
    CREB also involved in Classical Conditioning of the gill withdrawal reflex
    CREB-1: activates genes in the cell nucleus that stimulate Synapse formation
    CREB-2: inhibits CREB-1

see also

Tags: neurobiology science
Superlink: 051 ☣Neurobiology 050 🧠Neuroscience
Learning in the Aplysia Californica
Gene
030 🧬Genetics

Source

Lernen (Course)
LTP - long term potentiation

Created: 14-10-24 17:38