Huntington’s disease start around the 40-50 years of age.
It is an hereditary and progressive neurodegenerative disease that causes chorea, neurobehavioral changes (irritability, impulsiveness, anhedonia, Anxiety, Depression, mania, and others) and eventually dementia.
Chorea are involuntary movements of brief duration, usually starting distal, non-rhytmic, abrupt and irregular. It is caused due to a specific mutation of the gene that codes for the protein Huntington, with autonomic dominate inheritance, and affecting the complete brain but with earlier and stronger degeneration of the Striatum.
Symptoms
Symptoms of Huntington’s disease can include:
- difficulty concentrating and memory lapses
- depression
- stumbling and clumsiness
- involuntary jerking or fidgety movements of the limbs and body
- mood swings and personality changes
- problems swallowing, speaking and breathing
- difficulty moving
see also
Tags: neuroscience science
Superlink: 050 🧠Neuroscience
Parkinson’s disease
Source
https://www.nhs.uk/conditions/huntingtons-disease/
Created: 01-06-24 14:06