Apples and Pears
Glucocorticoids trigger fat cells to make an Enzymee that breaks down the circulating nutrients into their storage forms, ideal for storing them for next winter. (Location 1300)
==fat cells located in your abdominal area, around your belly, are known as “visceral” fat==. Fill up those fat cells with fat, without depositing much fat elsewhere in your body, and you take on an “apple” shape. In contrast, fat cells around your rear end form “gluteal” fat. Fill those up preferentially with fat and you take on a “pear” shape, being round-bottomed. (Location 1302)
glucocorticoids stimulate fat deposition, they do it preferentially in the abdomen, promoting apple-shaped obesity. This even occurs in monkeys. The pattern arises because abdominal fat cells are more sensitive to glucocorticoids than are gluteal fat cells; the former have more receptors that respond to glucocorticoids by activating those fat-storing enzymes. Furthermore, glucocorticoids only do this in the presence of high Insulin levels. (Location 1308)
Take some extremely applish people and some very peary ones. Match them for weight, and it’s the apples who are at risk for metabolic and cardiovascular disease. Among other reasons, this is probably because fat released from abdominal fat cells more readily finds its way to the Liver (in contrast to fat from gluteal fat stores, which gets dispersed more equally throughout the body), where it is converted into Glucose, setting you up for elevated blood sugar and insulin resistance. (Location 1316)
Not only do the Oreos taste good, but by reducing the Stress-Response, they make you feel good as well. (Location 1326)
see also
Tags: science medicine biology
Superlink: 091 🏃Body and Medicine, 090 🌱Biology, 051 ☣Neurobiology
Source
5 Ulcers The Runs and Hot Fudge Sundaes
Created: 03-09-22 15:44