a presentation for the course “Introduction to Sleep and Dreams.”
Student Presentation 4 - Memory and other functions of sleep (and what happens without sleep) (questions to Katharina)
Please include:
Memory function of sleep
(Metabolite) clearance
Consequences of sleep deprivation
Other functions (learning, emotional processing)
May include: whatever else you find interesting, e.g. Targeted memory reactivation (current study project)
test
Memory Function of Sleep
Metabolite Clearance
during the day toxic substances are released:
β-amyloid (Aβ) (antimicrobic, ),
during sleep, anaesthesia:
60% increase in the interstitial space
α-synuclein (transports synaptic vesicles (therefore neurotransmitters in those vesicles))
and tau (stabilisation of microtubules)
Why? → Aβ is a byproduct
What do they do? → degenerating, leading to cell death
How are they washed away? → ISF and CSF
How does this occur during the night? ISF is widened by 60%, less pressure and therefore more exchange
Consequences of Sleep Deprivation
Transclude of Why-We-Sleep#^00ab4e
Other Functions (Learning, Emotional Processing)
Xie, L., Kang, H., Xu, Q., Chen, M. J., Liao, Y., Thiyagarajan, M., Christensen, D. J., Nicholson, C., Iliff, J. J., Takano, T., Deane, R., & Nedergaard, M. (2013). Sleep Drives Metabolite Clearance from the Adult Brain. Science (New York, N.Y.), 342(6156). https://doi.org/10.1126/science.1241224
see also
Tags: neuroscience science
Superlink: 050 🧠Neuroscience
410 👨💻Uni und Lernen
Source
Created: 30-01-24 12:38